Multiple chronic diseases increase the risk of dementia, study suggests

Santo André, SP (Folhapress) – A study of greater than 200,000 Britons has linked multimorbidity with an elevated risk of dementia. The findings by medical doctors in the UK and Germany have been revealed this week in the scientific journal JAMA Open Network (the Journal of the American Medical Association).

In normal, multimorbidity is when the similar particular person has a number of chronic diseases. Depending on the idea, it may be thought-about from two or extra diseases.

“You know it is the affected person who has diabetes, hypertension, bronchial asthma,” says Diogo Haddad, a neurologist at Alemao Oswaldo Cruz Hospital.

The researchers matched ladies and men who didn’t have dementia and have been no less than 60 years previous to comply with up for 15 years — the common was 11.8 years. Information from the UK Biobank, a database linked to the British public well being system, collected between 2006 and 2010 was used.

During this era, 6,182 contributors developed dementia. The incidence fee was 1.87 per 1,000 individuals with out a number of diseases and three.41 for these with a number of diseases.

Patients with a number of well being issues have been non-white older girls with low schooling and dwelling in poor areas of the UK.

“Studies have scientifically confirmed the concept that sufferers who’ve a number of diseases have the next risk of creating dementia, particularly Alzheimer’s, all through their lives”, analyzes Haddad.

“Based on this, I can say that if you happen to take excellent care of hypertension and diabetes or stop these diseases, you might be instantly stopping the dementia course of,” he says.

Research has additionally identified that sufferers with out genetic risk elements, however with comorbidities, have the next risk of creating dementia than sufferers with out a number of chronic diseases.

“Many occasions individuals have the concept that dementia and Alzheimer’s specifically have a novel and solely genetic hyperlink. This isn’t the case. The illness is multifactorial”, explains the physician.

Other risk elements For Claudia Kimi Suemoto, professor of geriatrics at FMUSP (School of Medicine, University of São Paulo), the article differs by exhibiting the most typical teams of diseases that increase the risk.

In girls that is the case with hypertension, diabetes and coronary coronary heart illness and ache, osteoporosis and dyspepsia. In males, the mixture of diabetes and hypertension is the best risk issue, along with the affiliation with coronary coronary heart illness, hypertension and stroke.

Maria Gabriela dos Santos Gilardi, neurologist at HCor and physician of neurology at the Department of Neurology at FMUSP, remembers that the quantity of comorbidities is expounded to the risk: the extra chronic the illness, the extra doubtless dementia is.

According to medical doctors, such diseases are at all times interconnected and should be identified to have the ability to perform therapy and thus stop different issues arising from them.

Prevention neurologist Maria Gabriela dos Santos Gilardi highlighted inhibition cues as a key discovering of the study. For medical doctors, this “has a higher impression on prevention as a result of by it we are able to enhance the identification of people who’re at excessive risk of creating dementia and, thus, work extra successfully to stop the illness”.

In phrases of public well being insurance policies, the study factors to treating diseases akin to diabetes and hypertension as a strategy to stop dementia.

“For Alzheimer’s, it’s extra vital to have high quality main public well being than to consider methods to introduce a genetic testing system”, confused neurologist Diogo Haddad.

“There are sure elements in illness: modifiable and irreversible. Aging, for instance, isn’t modifiable. On the different hand, hypertension, diabetes, smoking, alcohol are doable elements to manage, modify and deal with”.

Leave a Comment

Your email address will not be published.